Michael breaks out from Fox River with his brother Lincoln and other convicts. Prison Break season 1 episode 22 found the gang on the run following their breakout.
But Lincoln was set up by some of the Company (an agency formed by corrupt government officials) guys, headed by General Jonathan Krantz. Structural Engineer Michael Scofield turns himself in to the Fox River Penitentiary in order to break out his brother Lincoln Burrows, who is on death row for the murder of the Vice President’s brother. On Prison Break Season 5 Episode 1 seven years after Michael Scofield was presumed dead, Lincoln Burrows asks Sara Tancredi to help him track down the truth.